Single subject task-related BOLD signal artifact in a real-time fMRI feedback paradigm.

ABSTRACT: Real-time functional magnetic resonance imaging (rtfMRI) has been proposed as a method of providing feedback to develop a participant's ability to control his or her own neuronal activity. However, this BOLD signal is vulnerable to contamination from nonneuronal sources that can also be shaped by the feedback provided. Here we illustrate an artifact found while training participants to control signal from an ROI in the insula. As the artifact was directly behind the eye and the experiment used an echo-planar imaging (EPI) sequence with phase encoding direction that included the orbits and the insula in the same line, we hypothesized that the artifact was due to eye motion. We demonstrate a reduced training effect when eyeball signal is regressed out of the data and reproduce the artifact w

SUBMITTER: Zhang X 

PROVIDER: S-EPMC6148359 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature