Lumbee traditional medicine: Neuroprotective activities of medicinal plants used to treat Parkinson's disease-related symptoms.

ABSTRACT:

Ethnopharmacological relevance

Parkinson's disease (PD) is a neurodegenerative disorder characterized by a loss of dopaminergic neurons in the substantia nigra pars compacta and the presence in surviving neurons of Lewy body inclusions enriched with aggregated forms of the presynaptic protein α-synuclein (aSyn). Although current therapies provide temporary symptomatic relief, they do not slow the underlying neurodegeneration in the midbrain. In this study, we analyzed contemporary herbal medicinal practices used by members of the Lumbee tribe to treat PD-related symptoms, in an effort to identify safe and effective herbal medicines to treat PD.

Aim of the study

The aims of this study were to (i) document medicinal plants used by Lumbee Indians to treat PD and PD-related symp

SUBMITTER: de Rus Jacquet A 

PROVIDER: S-EPMC6149226 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature