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Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity.

ABSTRACT: The fermentation and isolation of metabolites produced by an endophytic fungus, which was identified as Phomopsis sp. FJBR-11, based on phylogenetic analysis, led to the identification of six compounds, including dothiorelones A-C, and H, and cytosporones C and U. Among these compounds, cytosporone U exhibited potent inhibitory activity against Tobacco mosaic virus (TMV). Moreover, the crude and a purified exopolysaccharide were proved to possess strong inhibitory effects against the virus infection.

SUBMITTER: Tan QW 

PROVIDER: S-EPMC6149851 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

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Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity.

Tan Qing-Wei QW   Fang Pei-Hua PH   Ni Jian-Cheng JC   Gao Fangluan F   Chen Qi-Jian QJ  

Molecules (Basel, Switzerland) 20171127 12

The fermentation and isolation of metabolites produced by an endophytic fungus, which was identified as <i>Phomopsis</i> sp. FJBR-11, based on phylogenetic analysis, led to the identification of six compounds, including dothiorelones A-C, and H, and cytosporones C and U. Among these compounds, cytosporone U exhibited potent inhibitory activity against <i>Tobacco mosaic virus</i> (TMV). Moreover, the crude and a purified exopolysaccharide were proved to possess strong inhibitory effects against t  ...[more]

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