The cortical structure of functional networks associated with age-related cognitive abilities in older adults.

ABSTRACT: Age and cortical structure are both associated with cognition, but characterizing this relationship remains a challenge. A popular approach is to use functional network organization of the cortex as an organizing principle for post-hoc interpretations of structural results. In the current study, we introduce two complimentary approaches to structural analyses that are guided by a-priori functional network maps. Specifically, we systematically investigated the relationship of cortical structure (thickness and surface area) of distinct functional networks to two cognitive domains sensitive to age-related decline thought to rely on both common and distinct processes (executive function and episodic memory) in older adults. We quantified the cortical structure of individual functional network'

SUBMITTER: Kranz MB 

PROVIDER: S-EPMC6150534 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature