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Key elements involved in Epstein-Barr virus-associated gastric cancer and their network regulation.


ABSTRACT:

SUBMITTER: Jing JJ 

PROVIDER: S-EPMC6151003 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Key elements involved in Epstein-Barr virus-associated gastric cancer and their network regulation.

Jing Jing-Jing JJ   Wang Ze-Yang ZY   Li Hao H   Sun Li-Ping LP   Yuan Yuan Y  

Cancer cell international 20180921


<h4>Background</h4>The molecular mechanism of Epstein-Barr virus (EBV)-associated gastric cancer (EBVaGC) remains elusive. A collection of molecular regulators including transcription factor and noncoding RNA (ncRNAs) may affect the carcinogenesis of EBVaGC by regulating the expression and function of key genes. In this study, integration of multi-level expression data and bioinformatics approach was used to identify key elements and their interactions involved in mechanism of EBVaGC and their n  ...[more]

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