Do comorbid social and other anxiety disorders predict outcomes during and after cognitive therapy for depression?

ABSTRACT:

Background

Cognitive therapy (CT) improves symptoms in adults with major depressive disorder (MDD) plus comorbid anxiety disorder, but the specific type of anxiety may influence outcomes. This study compared CT outcomes among adults with MDD plus social, other, or no comorbid anxiety disorders.

Methods

Outpatients with recurrent MDD (N = 523, including 87 with social and 110 with other comorbid anxiety disorders) received acute-phase CT. Higher risk responders (n = 241 with partial or unstable response) were randomized to 8 months of continuation treatment (CT or clinical management plus fluoxetine or pill placebo), followed by 24 months of assessment. Lower risk responders (n = 49) were assessed for 32 months without additional research treatment. Depression, anxiety sympto

SUBMITTER: Vittengl JR 

PROVIDER: S-EPMC6151272 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature