Silver Oxide Coatings with High Silver-Ion Elution Rates and Characterization of Bactericidal Activity.

ABSTRACT: This paper reports the synthesis and characterization of silver oxide films for use as bactericidal coatings. Synthesis parameters, dissolution/elution rate, and bactericidal efficacy are reported. Synthesis conditions were developed to create AgO, Ag₂O, or mixtures of AgO and Ag₂O on surfaces by reactive magnetron sputtering. The coatings demonstrate strong adhesion to many substrate materials and impede the growth of all bacterial strains tested. The coatings are effective in killing Escherichia coli and Staphylococcus aureus, demonstrating a clear zone-of-inhibition against bacteria growing on solid media and the ability to rapidly inhibit bacterial growth in planktonic culture. Additionally, the coatings exhibit very high elution of silver ions under conditions that mimic

SUBMITTER: Goderecci SS 

PROVIDER: S-EPMC6151401 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature