Effects on Rotational Dynamics of Azo and Hydrazodicarboxamide-Based Rotaxanes.

ABSTRACT: The synthesis of novel hydrogen-bonded [2]rotaxanes having two pyridine rings in the macrocycle and azo- and hydrazodicarboxamide-based templates decorated with four cyclohexyl groups is described. The different affinity of the binding sites for the benzylic amide macrocycle and the formation of programmed non-covalent interactions between the interlocked components have an important effect on the dynamic behavior of these compounds. Having this in mind, the chemical interconversion between the azo and hydrazo forms of the [2]rotaxane was investigated to provide a chemically-driven interlocked system enable to switch its circumrotation rate as a function of the oxidation level of the binding site. Different structural modifications were carried out to further functionalize the nitrogen of

SUBMITTER: Saura-Sanmartin A 

PROVIDER: S-EPMC6152038 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature