Role of Dimensionality in Predicting the Spontaneous Behavior of the Brain Using the Classical Ising Model and the Ising Model Implemented on a Structural Connectome.

ABSTRACT: There is accumulating evidence that spontaneous fluctuations of the brain are sustained by a structural architecture of axonal fiber bundles. Various models have been used to investigate this structure-function relationship. In this work, we implemented the Ising model using the number of fibers between each pair of brain regions as input. The output of the Ising model simulations on a structural connectome was then compared with empirical functional connectivity data. A simpler two-dimensional classical Ising model was used as the baseline model for comparison purpose. Thermodynamic properties, such as the magnetic susceptibility and the specific heat, illustrated a phase transition from an ordered phase to a disordered phase at the critical temperature. Despite the differences between th

SUBMITTER: Abeyasinghe PM 

PROVIDER: S-EPMC6152861 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature