Racial Disparities in Lung Cancer Survival: The Contribution of Stage, Treatment, and Ancestry.

ABSTRACT:

Introduction

Lung cancer is a leading cause of cancer-related death worldwide. Racial disparities in lung cancer survival exist between blacks and whites, yet they are limited by categorical definitions of race. We sought to examine the impact of African ancestry on overall survival among blacks and whites with NSCLC cases.

Methods

Incident cases of NSCLC in blacks and whites from the prospective Southern Community Cohort Study (N = 425) were identified through linkage with state cancer registries in 12 southern states. Vital status was determined by linkage with the National Death Index and Social Security Administration. We evaluated the impact of African ancestry (as estimated by using genome-wide ancestry-informative markers) on overall survival by calculating the time-d

SUBMITTER: Jones CC 

PROVIDER: S-EPMC6153049 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature