Cognitive Impairment in Non-Dialysis-Dependent CKD and the Transition to Dialysis: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.

ABSTRACT:

Background

Advanced chronic kidney disease is associated with elevated risk for cognitive impairment. However, it is not known whether and how cognitive impairment is associated with planning and preparation for end-stage renal disease.

Study design

Retrospective observational study.

Setting & participants

630 adults participating in the CRIC (Chronic Renal Insufficiency Cohort) Study who had cognitive assessments in late-stage CKD, defined as estimated glome-rular filtration rate ≤ 20mL/min/1.73m², and subsequently initiated maintenance dialysis therapy.

Predictor

Predialysis cognitive impairment, defined as a score on the Modified Mini-Mental State Examination lower than previously derived age-based threshold scores. Covariates included age, race/e

SUBMITTER: Harhay MN 

PROVIDER: S-EPMC6153064 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature