Biomimetic Synthesis of Resveratrol Trimers Catalyzed by Horseradish Peroxidase.

ABSTRACT: Biotransformation of trans-resveratrol and synthetic (±)-ε-viniferin in aqueous acetone using horseradish peroxidase and hydrogen peroxide as oxidants resulted in the isolation of two new resveratrol trimers (3 and 4), one new resveratrol derivative (5) with a dihydrobenzofuran skeleton, together with two known stilbene trimers (6 and 7), and six known stilbene dimers (8-13). Their structures and relative configurations were identified through spectral analysis and possible formation mechanisms were also discussed. Among these oligomers, trimers 6 and 7 were obtained for the first time through direct transformation from resveratrol. Results indicated that this reaction is suitable for the preparation of resveratrol oligo

SUBMITTER: Zhang JQ 

PROVIDER: S-EPMC6154677 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature