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MEG resting-state oscillations and their relationship to clinical symptoms in schizophrenia.


ABSTRACT: Neuroimaging studies suggest that schizophrenia is characterized by disturbances in oscillatory activity, although at present it remains unclear whether these neural abnormalities are driven by dimensions of symptomatology. Examining different subgroups of patients based on their symptomatology is thus very informative in understanding the role of neural oscillation patterns in schizophrenia. In the present study we examined whether neural oscillations in the delta, theta, alpha, beta and gamma bands correlate with positive and negative symptoms in individuals with schizophrenia (SZ) during rest. Resting-state brain activity of 39 SZ and 25 neurotypical controls was recorded using magnetoencephalography. Patients were categorized based on the severity of their positive and negative symptom

SUBMITTER: Zeev-Wolf M 

PROVIDER: S-EPMC6154766 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature