Quantifying the impact of social groups and vaccination on inequalities in infectious diseases using a mathematical model.

ABSTRACT:

Background

Social and cultural disparities in infectious disease burden are caused by systematic differences between communities. Some differences have a direct and proportional impact on disease burden, such as health-seeking behaviour and severity of infection. Other differences-such as contact rates and susceptibility-affect the risk of transmission, where the impact on disease burden is indirect and remains unclear. Furthermore, the concomitant impact of vaccination on such inequalities is not well understood.

Methods

To quantify the role of differences in transmission on inequalities and the subsequent impact of vaccination, we developed a novel mathematical framework that integrates a mechanistic model of disease transmission with a demographic model of social structur

SUBMITTER: Munday JD 

PROVIDER: S-EPMC6156851 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature