Resistant Streptococcus pneumoniae strains in children with acute otitis media- high risk of persistent colonization after treatment.

ABSTRACT:

Background

Despite advances in the development of pneumococcal conjugate vaccines, acute otitis media (AOM) is a common childhood infection, caused mainly by Streptococcus pneumoniae. It has been suggested that persistence of pneumococcal nasopharyngeal carriage is a risk factor for subsequent recurrent infections.

Methods

In this study we evaluate the relationship between 55 pneumococcal strains obtained from nasopharynx/oropharynx (NP/OP) and middle ear fluid (MEF) of 62 children, aged between 1 and 16 years, during AOM (including recurrent/treatment failure AOM, and post-treatment visits), based on their phenotypic and genotypic characteristics performed by analyses of serotype, antibiotic susceptibility patterns and multilocus sequence typing.

Results

S.pneumoniae

SUBMITTER: Korona-Glowniak I 

PROVIDER: S-EPMC6156860 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature