Aqueous solutions of surface-active ionic liquids: remarkable alternative solvents to improve the solubility of triterpenic acids and their extraction from biomass.

ABSTRACT: Triterpenic acids (TTAs) are well known for their relevant biological properties and have been facing an increasing interest for nutraceutical and pharmaceutical applications. To overcome the concerns associated to the commonly used volatile organic solvents for their extraction from biomass, here we investigate the potential of aqueous solutions of ionic liquids (ILs) as alternative solvents. The solubility of ursolic acid (UA) was firstly determined in several aqueous solutions of ILs (hydrotropes or surface-active) at 30°C to appraise the dissolution phenomenon. Conventional surfactants were also investigated for comparison purposes. The collected data reveal a remarkable enhancement in the solubility of UA (8 orders of magnitude) in surface-active ILs aqueous solutions when compared to

SUBMITTER: de Faria ELP 

PROVIDER: S-EPMC6157723 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature