Outdoor particulate matter (PM10) exposure and lung cancer risk in the EAGLE study.

ABSTRACT:

Objective

Cohort studies in Europe, but not in North-America, showed an association between exposure to outdoor particulate matter with aerodynamic diameter ≤10 μm (PM10) and lung cancer risk. Only a case-control study on lung cancer and PM10 in South Korea has so far been performed. For the first time in Europe we analyzed quantitatively this association using a case-control study design in highly polluted areas in Italy.

Methods

The Environment And Genetics in Lung cancer Etiology (EAGLE) study, a population-based case-control study performed in the period 2002-2005 in the Lombardy Region, north-west Italy, enrolled 2099 cases and 2120 controls frequency-matched for area of residence, gender, and age. For this study we selected subjects with complete active and passive smo

SUBMITTER: Consonni D 

PROVIDER: S-EPMC6157824 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature