Association of anemia and hemoglobin decrease during acute stroke treatment with infarct growth and clinical outcome.

ABSTRACT:

Background and purpose

Anemia is associated with worse outcome in stroke, but the impact of anemia with intravenous thrombolysis or endovascular therapy has hardly been delineated. The aim of this study was to analyze the role of anemia on infarct evolution and outcome after acute stroke treatment.

Methods

1158 patients from Bern and 321 from Los Angeles were included. Baseline data and 3 months outcome assessed with the modified Rankin Scale were recorded prospectively. Baseline DWI lesion volumes were measured in 345 patients and both baseline and final infarct volumes in 180 patients using CT or MRI. Multivariable and linear regression analysis were used to determine predictors of outcome and infarct growth.

Results

712 patients underwent endovascular treatment and

SUBMITTER: Bellwald S 

PROVIDER: S-EPMC6157859 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature