Dysregulated behavioral responses to hedonic probes among youth with depression histories and their high-risk siblings.

ABSTRACT: Affect dysregulation in response to rewarding stimuli has been proposed as a vulnerability factor for major depressive disorder (MDD). However, it remains unclear how affective behavioral dynamics may be altered among individuals who are at high risk for depression but not currently depressed. We examined the dynamics of affective facial behavior during hedonic probes among 3 groups of adolescents: remitted probands who had histories of childhood-onset MDD (n = 187), never-depressed siblings of probands (high familial risk; n = 207), and healthy controls (n = 166). Participants' happy and sad facial expressions were coded during 3 hedonic laboratory tasks: receiving a preferred prize, describing a positive autobiographical memory, and watching a humorous film. Happy and sad behavioral dyna

SUBMITTER: Panaite V 

PROVIDER: S-EPMC6158125 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature