Cellular responses to in vitro exposures to β-blocking pharmaceuticals in hard clams and Eastern oysters.

ABSTRACT: Increased consumption and improper disposal of prescription medication, such as beta (β)-blockers, contribute to their introduction into waterways and may pose threats to non-target aquatic organisms. There has been rising concern about the impacts of these prescription drugs on coastal ecosystems, especially because wastewater treatment plants are not designed to eliminate them from the discharge. Few studies have characterized the sublethal effects of β-blocker exposures in marine invertebrates. The overall aim of our research is to identify cellular responses of two commercially important filter-feeding marine bivalves, hard clams (Mercenaria mercenaria) and Eastern oysters (Crassostrea virginica), upon exposures to two β-blocker drugs, propranolol and metoprolol. In vitro exposures wit

SUBMITTER: Khan B 

PROVIDER: S-EPMC6158783 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature