Comparative genome analysis provides deep insights into Aeromonas hydrophila taxonomy and virulence-related factors.

ABSTRACT:

Background

Aeromonas hydrophila is a potential zoonotic pathogen and primary fish pathogen. With overlapping characteristics, multiple isolates are often mislabelled and misclassified. Moreover, the potential pathogenic factors among the publicly available genomes in A. hydrophila strains of different origins have not yet been investigated.

Results

To identify the valid strains of A. hydrophila and their pathogenic factors, we performed a pan-genomic study. It revealed that there were 13 mislabelled strains and 49 valid strains that were further verified by Average nucleotide identity (ANI), digital DNA-DNA hybridization (dDDH) and in silico multiple locus strain typing (MLST). Multiple numbers of phages were detected among the strains and among them Aeromonas phi 018 was fr

SUBMITTER: Awan F 

PROVIDER: S-EPMC6158803 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature