Long-Term Consequences of Worsened Poststroke Status in Patients With Premorbid Disability.

ABSTRACT: Background and Purpose- Patients with premorbid disability, generally defined as modified Rankin Scale (mRS) score ≥2, are often excluded from trials of acute stroke therapies. However, increased disability in such patients will adversely affect long-term outcomes if treatments are withheld in routine practice. We assessed the extent to which increased disability poststroke influences 5-year mortality, institutionalization, and costs in premorbidly disabled patients. Methods- In a population-based, prospective cohort of patients with ischemic stroke (OXVASC [Oxford Vascular Study], 2002-2014), we tracked mortality, institutionalization, and healthcare/social-care costs during follow-up. We compared 5-year mortality and poststroke institutionalization (Cox regressions) and 5-year healthcare

SUBMITTER: Ganesh A 

PROVIDER: S-EPMC6159688 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature