Treating acute fatty liver of pregnancy with artificial liver support therapy: Systematic review.

ABSTRACT:

Background

Acute fatty liver of pregnancy (AFLP) is a serious disease with high mortality. Recent data suggest that postpartum application of artificial liver support therapy (ALST) in AFLP management improves disease outcome. In current study, we tend to further evaluate whether the type, the timing, and the number of postpartum ALST sessions and other clinical factors including complications and liver and renal function will influence disease outcome in ALST era.

Methods

Medical records of 15 AFLP patients having postpartum ALST in our hospital from 2010 to 2016 were first retrospectively reviewed. A systematic review and statistical analysis was then conducted with our cases and those having postpartum ALST reported in PubMed, Embase, Cochrane, and ClinicalTrials.gov till

SUBMITTER: Wu Z 

PROVIDER: S-EPMC6160087 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature