Asthma is associated with carotid arterial injury in children: The Childhood Origins of Asthma (COAST) Cohort.

ABSTRACT:

Background

Asthma is associated with an increased cardiovascular disease (CVD) risk in adults, but the impact of asthma and atopic conditions on CVD risk in children is less well established. We hypothesized that children in the Childhood Origins of Asthma (COAST) Cohort with asthma and atopic conditions would have early carotid arterial injury.

Methods

The COAST study is a longitudinal birth cohort of children at increased risk of developing asthma. Children underwent ultrasonography measuring far wall right carotid bifurcation (RCB) and common carotid artery (RCCA) intima-media thickness (IMT; a measure of arterial injury). Multivariable linear regression models adjusted for age, gender, race, blood pressure, and body-mass index were used to assess associations of asthma a

SUBMITTER: Tattersall MC 

PROVIDER: S-EPMC6160166 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature