MRI in predicting conversion to multiple sclerosis within 1 year.

ABSTRACT:

Objectives

Most patients diagnosed with multiple sclerosis (MS) present with a clinically isolated syndrome (CIS). We aimed to verify previously reported imaging and clinical findings, and to identify new MRI findings that might serve as prognostic factors for a second clinical episode or a change in the MRI scan during the first year following a CIS.

Materials and methods

We identified from our medical records, 46 individuals who presented with an episode of CIS, which was followed clinically and with imaging studies. A neuroradiologist blinded to the clinical data reviewed the images and recorded the number of lesions, lesion location, and the largest longitudinal diameter of the lesion.

Results

One year after the first MRI, 25 (54%) patients had progressed to MS. T

SUBMITTER: Eran A 

PROVIDER: S-EPMC6160649 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature