Circulating endothelial progenitor cells and endothelial cells in moyamoya disease.

ABSTRACT:

Introduction

There is no well-recognized biomarker for accurately predicting outcome in the presence of moyamoya disease (MMD), a progressive occlusive cerebrovascular disease of the internal carotid arteries or their branches. The aim of this study was to investigate the presence of endothelial progenitor cells (EPCs) and circulating endothelial cells (CECs) in MMD and correlate the findings with clinical features.

Methods

Patients with MMD (n = 66) were compared with healthy controls (n = 81). Blood samples were obtained from an antecubital vein and analyzed using flow cytometry. EPCs were defined as CD31⁺ CD45^dim CD34^br CD133⁺ and CECs as CD31^br CD45^- CD34^dim CD133^- . Univariate and mu

SUBMITTER: Bao XY 

PROVIDER: S-EPMC6160662 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature