Multivariable Artificial Pancreas for Various Exercise Types and Intensities.

ABSTRACT:

Background

Exercise challenges people with type 1 diabetes in controlling their glucose concentration (GC). A multivariable adaptive artificial pancreas (MAAP) may lessen the burden.

Methods

The MAAP operates without any user input and computes insulin based on continuous glucose monitor and physical activity signals. To analyze performance, 18 60-h closed-loop experiments with 96 exercise sessions with three different protocols were completed. Each day, the subjects completed one resistance and one treadmill exercise (moderate continuous training [MCT] or high-intensity interval training [HIIT]). The primary outcome is time spent in each glycemic range during the exercise + recovery period. Secondary measures include average GC and average change in GC during each exercise

SUBMITTER: Turksoy K 

PROVIDER: S-EPMC6161329 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature