The use of a virtual patient to follow pleural pressure changes associated with therapeutic thoracentesis.

ABSTRACT:

Purpose

Influence of therapeutic thoracentesis on the pleural pressure (Pp) has been discussed in many clinical studies, however reasons of Pp changes are not precisely established. The aim of the study was to use a previously elaborated virtual cardiopulmonary patient (VP) in analysis of impact of physiological factors on Pp during the procedure.

Methods

Simulations were performed on VP with default values of parameters for which VP simulated the respiratory system of the average 50-year-old healthy Polish woman according to spirometric examination. Alterations of Pp and the amplitude of Pp changes related to breathing (AP) were analyzed. Model parameters related to chosen factors were deviated from their default values to analyze the degree of their impact on Pp and AP. Th

SUBMITTER: Golczewski T 

PROVIDER: S-EPMC6161568 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature