Clinical manifestations of dengue in relation to dengue serotype and genotype in Malaysia: A retrospective observational study.

ABSTRACT:

Background

Malaysia experienced an unprecedented dengue outbreak from the year 2014 to 2016 that resulted in an enormous increase in the number of cases and mortality as compared to previous years. The causes that attribute to a dengue outbreak can be multifactorial. Viral factors, such as dengue serotype and genotype, are the components of interest in this study. Although only a small number of studies investigated the association between the serotype of dengue virus and clinical manifestations, none of these studies included analyses on dengue genotypes. The present study aims to investigate dengue serotype and genotype-specific clinical characteristics among dengue fever and severe dengue cases from two Malaysian tertiary hospitals between 2014 and mid-2017.

Methodology and p

SUBMITTER: Suppiah J 

PROVIDER: S-EPMC6161924 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature