Cigarette smoking and thyroid cancer risk: a cohort study.

ABSTRACT:

Background

We evaluated the association between smoking status and thyroid cancer risk and whether this association is mediated by body mass index (BMI) and thyroid-stimulating hormone (TSH).

Methods

We performed a cohort study of 96,855 Korean adults who were followed annually or biennially for a median of 5.9 years.

Results

During 511,052.9 person-years of follow-up, 1,250 participants developed thyroid cancer. In men, we observed a dose-dependent inverse association between current smoking, pack-years, and thyroid cancer. After adjustment for confounders, adjusted hazard ratios (95% confidence intervals) for thyroid cancer comparing current and former smokers to never smokers were 0.58 (0.45-0.75) and 0.93 (0.73-1.18), respectively. After further adjustment for BMI

SUBMITTER: Cho A 

PROVIDER: S-EPMC6162293 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature