Excess body weight, weight gain and obesity-related cancer risk in women in Norway: the Norwegian Women and Cancer study.

ABSTRACT:

Background

Excess body weight and weight gain have been reported to independently increase the risk of several cancers. There are few published studies in nationally representative populations of women on specific, 'obesity-related' cancers in relation to prior weight change and relevant confounders.

Methods

Based on self-reported anthropometry, we prospectively assessed body mass index (BMI), weight change over 6 years and subsequent obesity-related cancer risk in the Norwegian Women and Cancer study. We used Cox proportional hazard models to calculate hazard ratios and restricted cubic splines to model potential non-linear dose-response relationships.

Results

Excess body weight increased the risk of overall obesity-related cancer, postmenopausal breast, colorectal,

SUBMITTER: da Silva M 

PROVIDER: S-EPMC6162329 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature