Ontology highlight
ABSTRACT:
SUBMITTER: Contu F
PROVIDER: S-EPMC6162537 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Contu Fabio F Rangel-Pozzo Aline A Trokajlo Peter P Wark Landon L Klewes Ludger L Johnson Nathalie A NA Petrogiannis-Haliotis Tina T Gartner John G JG Garini Yuval Y Vanni Roberta R Knecht Hans H Mai Sabine S
Cancers 20180824 9
Classical Hodgkin's lymphoma (cHL) is a B-Cell lymphoma comprised of mononuclear Hodgkin cells (H) and bi- to multi-nucleated Reed-Sternberg (RS) cells. Previous studies revealed that H and RS cells express lamin A/C, a component of the lamina of the nuclear matrix. Since no information was available about the three-dimensional (3D) expression patterns of lamin A/C in H and RS cells, we analyzed the 3D spatial organization of lamin in such cells, using 3D fluorescent microscopy. H and RS cells f ...[more]