Association between Cigarette Smoking Status and Composition of Gut Microbiota: Population-Based Cross-Sectional Study.

ABSTRACT: There have been few large-scale studies on the relationship between smoking and gut microbiota. We investigated the relationship between smoking status and the composition of gut microbiota. This was a population-based cross-sectional study using Healthcare Screening Center cohort data. A total of 758 men were selected and divided into three groups: never (n = 288), former (n = 267), and current smokers (n = 203). Among the three groups, there was no difference in alpha diversity, however, Jaccard-based beta diversity showed significant difference (p = 0.015). Pairwise permutational multivariate analysis of variance (PERMANOVA) tests between never and former smokers did not show a difference; however, there was significant difference between never and current sm

SUBMITTER: Lee SH 

PROVIDER: S-EPMC6162563 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature