Postprandial Hypertriglyceridemia Is Associated with the Variant 54 Threonine FABP2 Gene.

ABSTRACT: Purpose: Fasting or postprandial hypertriglyceridemia is considered an independent cardiovascular disease (CVD) risk factor. The intestinal fatty acid binding protein (FABP2) is involved in the intracellular transport and metabolism of fatty acids. The presence of the Ala54Thr polymorphism of the FABP2 gene appears to be involved in postprandial hypertriglyceridemia. We explored the possible association of the Ala54Thr polymorphism with fat intolerance in apparently healthy, fasting, normolipidemic subjects with normal body-mass index and without diabetes. Methodology: A total of 158 apparently healthy individuals were classified as fat tolerant (n = 123) or intolerant (n = 35) according to their response (plasma triglycerides) to an oral abbreviated tolerance test with blood samples taken

SUBMITTER: Garces Da Silva MF 

PROVIDER: S-EPMC6162774 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature