Genomes from uncultivated prokaryotes: a comparison of metagenome-assembled and single-amplified genomes.

ABSTRACT:

Background

Prokaryotes dominate the biosphere and regulate biogeochemical processes essential to all life. Yet, our knowledge about their biology is for the most part limited to the minority that has been successfully cultured. Molecular techniques now allow for obtaining genome sequences of uncultivated prokaryotic taxa, facilitating in-depth analyses that may ultimately improve our understanding of these key organisms.

Results

We compared results from two culture-independent strategies for recovering bacterial genomes: single-amplified genomes and metagenome-assembled genomes. Single-amplified genomes were obtained from samples collected at an offshore station in the Baltic Sea Proper and compared to previously obtained metagenome-assembled genomes from a time series at th

SUBMITTER: Alneberg J 

PROVIDER: S-EPMC6162917 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature