Contrasting In Vitro Apatite Growth from Bioactive Glass Surfaces with that of Spontaneous Precipitation.

ABSTRACT: Body-fluid-exposed bioactive glasses (BGs) integrate with living tissues due to the formation of a biomimetic surface layer of calcium hydroxy-carbonate apatite (HCA) with a close composition to bone mineral. Vast efforts have been spent to understand the mechanisms underlying in vitro apatite mineralization, as either formed by direct precipitation from supersaturated solutions, or from BG substrates in a simulated body fluid (SBF). Formally, these two scenarios are distinct and have hitherto been discussed as such. Herein, we contrast them and identify several shared features. We monitored the formation of amorphous calcium phosphate (ACP) and its crystallization into HCA from a Na 2 O⁻CaO⁻SiO 2 ⁻P 2 O 5 glass exposed to SBF for variable periods out to 28 days. The HCA growth was assesse

SUBMITTER: Yu Y 

PROVIDER: S-EPMC6164250 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature