Royal Jelly Delays Motor Functional Impairment During Aging in Genetically Heterogeneous Male Mice.

ABSTRACT: Aging is associated with motor disorders that decrease the quality of life (QOL). Royal jelly (RJ), used as a dietary supplement, has shown various health benefits and, therefore, it has the potential to improve the QOL during aging. We have previously developed protease enzyme-treated RJ to avoid the anaphylactic response induced by RJ supplementation. However, the effects of a lifelong treatment with RJ on normal aging have not been fully clarified. In this study, we investigated the effects of enzyme-untreated RJ (NRJ) and enzyme-treated RJ (ERJ) on the aging process focusing on motor functions, by using a genetically heterogeneous (HET) mouse model experimentally endowed with genetic diversity. We performed four different physical performance tests (grip strength, wire hang, horizontal

SUBMITTER: Okumura N 

PROVIDER: S-EPMC6164577 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature