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Exopolysaccharide from Marine Bacillus velezensis MHM3 Induces Apoptosis of Human Breast Cancer MCF-7 Cells through a Mitochondrial Pathway

ABSTRACT: Objective: The production of new natural pharmaceutical agents that increase the efficiency of chemotherapy

SUBMITTER: Mahgoub AM

PROVIDER: S-EPMC6165642 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Exopolysaccharide from Marine Bacillus velezensis MHM3 Induces Apoptosis of Human Breast Cancer MCF-7 Cells through a Mitochondrial Pathway

Mahgoub Ahmed M AM Mahmoud Manal G MG Selim Manal S MS EL Awady Mohamed E ME

Asian Pacific journal of cancer prevention : APJCP 20180727 7

Objective: The production of new natural pharmaceutical agents that increase the efficiency of chemotherapy without affecting the normal cells is the goal of all researchers. Therefore, the present study expects to evaluate the antioxidant and anticancer studies against MCF-7 cell lines of EPS produced by novel Egyptian marine bacterial strain. Methods: Marine bacterium was isolated, purified and identified by 16S rRNA gene amplification and sequence analyses. MHMEPS (the produced EPS) was analy ...[more]

PMID: 30051679

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