Clinical outcomes of patients with major depressive disorder treated with either duloxetine, escitalopram, fluoxetine, paroxetine, or sertraline.

ABSTRACT:

Purpose

To compare treatment outcomes in patients with major depressive disorder treated with duloxetine, escitalopram, fluoxetine, paroxetine, or sertraline for up to 6 months.

Patients and methods

Data were taken from a 6-month prospective, observational study that included 1,549 major depressive disorder patients without sexual dysfunction in 12 countries. We report the overall results and those from Asian countries. Depression severity was measured using the Clinical Global Impression and the 16-item Quick Inventory of Depressive Symptomatology Self-Report (QIDS-SR₁₆). Clinical and functional remissions were defined as having a QIDS-SR₁₆ <6, and as having a rating of <3 on all three Sheehan Disability Scale items and no reduced productivity, respect

SUBMITTER: Huang J 

PROVIDER: S-EPMC6165742 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature