Novel photoactivatable substrates for Renilla luciferase imaging in vitro and in vivo.

ABSTRACT: To develop a photoactivatable bioluminescence imaging technique, a set of high and efficient photoactivatable substrates for Renilla luciferase has been well designed and synthesized. Surprisingly, all of them could release the free luciferin that presented robust bioluminescent signals ex vivo and in living animals after UV irradiation at 365 nm.

SUBMITTER: Zhang C 

PROVIDER: S-EPMC6165844 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature