Prediction of readmissions and mortality in patients with heart failure: lessons from the IMPEDANCE-HF extended trial.

ABSTRACT:

Aims

Readmissions for heart failure (HF) are a major burden. We aimed to assess whether the extent of improvement in pulmonary fluid content (ΔPC) during HF hospitalization evaluated by lung impedance (LI), or indirectly by other clinical and laboratory parameters, predicts readmissions.

Methods and results

The present study is based on pre-defined secondary analysis of the IMPEDANCE-HF extended trial comprising 266 HF patients at New York Heart Association Class II-IV and left ventricular ejection fraction ≤ 35% randomized to LI-guided or conventional therapy during long-term follow-up. Lung impedance-guided patients were followed for 58 ± 36 months and the control patients for 46 ± 34 months (P < 0.01) accounting for 253 and 478 HF hospitalizations, respectively (P < 0.01)

SUBMITTER: Kleiner Shochat M 

PROVIDER: S-EPMC6165944 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature