Optical Temperature Sensing With Infrared Excited Upconversion Nanoparticles.

ABSTRACT: Upconversion Nanoparticles (UCNPs) enable direct measurement of the local temperature with high temporal and thermal resolution and sensitivity. Current studies focusing on small animals and cellular systems, based on continuous wave (CW) infrared excitation sources, typically lead to localized thermal heating. However, the effects of upconversion bioimaging at the molecular scale, where higher infrared intensities under a tightly focused excitation beam, coupled with pulsed excitation to provide higher peak powers, is not well understood. We report on the feasibility of 800 and 980 nm excited UCNPs in thermal sensing under pulsed excitation. The UCNPs report temperature ratiometrically with sensitivities in the 1 × 10^-4 K^-1 range under both excitation wavelengths. Ou

SUBMITTER: Green K 

PROVIDER: S-EPMC6166686 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature