Dataset Information

Trends in Bone Marrow Sampling and Core Biopsy Specimen Adequacy in the United States and Canada: A Multicenter Study.

ABSTRACT:

Objectives

To assess bone marrow (BM) sampling in academic medical centers.

Methods

Data from 6,374 BM samples obtained in 32 centers in 2001 and 2011, including core length (CL), were analyzed.

Results

BM included a biopsy (BMB; 93%) specimen, aspirate (BMA; 92%) specimen, or both (83%). The median (SD) CL was 12 (8.5) mm, and evaluable marrow was 9 (7.6) mm. Tissue contraction due to processing was 15%. BMB specimens were longer in adults younger than 60 years, men, and bilateral, staging, and baseline samples. Only 4% of BMB and 2% of BMB/BMA samples were deemed inadequate for diagnosis. BM for plasma cell dyscrasias, nonphysician operators, and ancillary studies usage increased, while bilateral sampling decreased over the decade. BM-related quality assurance programs are infrequent.

Conclusions

CL is shorter than recommended and varies with patient age and sex, clinical circumstances, and center experience. While pathologists render diagnoses on most cases irrespective of CL, BMB yield improvement is desirable.

SUBMITTER: Merzianu M

PROVIDER: S-EPMC6166687 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Publications

Trends in Bone Marrow Sampling and Core Biopsy Specimen Adequacy in the United States and Canada: A Multicenter Study.

Merzianu Mihai M Groman Adrienne A Hutson Alan A Cotta Claudiu C Brynes Russell K RK Orazi Attilio A Reddy Vishnu V Teruya-Feldstein Julie J Amre Ramila R Balasubramanian Manjula M Brandao Guilherme G Cherian Sindhu S Courville Elizabeth E Czuchlewski David D Fan Guang G Grier David D Hoehn Daniela D Inamdar Kedar V KV Juskevicius Ridas R Kaur Prabhjot P Lazarchick John J Lewis Michael R MR Miles Rodney R RR Myers Jerome B JB Nasr Michel R MR Qureishi Hina N HN Olteanu Horatiu H Robu Valentin G VG Salaru Gratian G Vajpayee Neerja N Vos Jeffrey J Zhang Ling L Zhang Shanxiang S Aye Le L Brega Elisa E Coad James E JE Grantham John J Ivelja Sinisa S McKenna Robert R Sultan Kieran K Wilding Gregory G Hutchison Robert R Peterson LoAnn L Cheney Richard T RT

American journal of clinical pathology 20181001 5

<h4>Objectives</h4>To assess bone marrow (BM) sampling in academic medical centers.<h4>Methods</h4>Data from 6,374 BM samples obtained in 32 centers in 2001 and 2011, including core length (CL), were analyzed.<h4>Results</h4>BM included a biopsy (BMB; 93%) specimen, aspirate (BMA; 92%) specimen, or both (83%). The median (SD) CL was 12 (8.5) mm, and evaluable marrow was 9 (7.6) mm. Tissue contraction due to processing was 15%. BMB specimens were longer in adults younger than 60 years, men, and b ...[more]

PMID: 30052721

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Dataset Information

Trends in Bone Marrow Sampling and Core Biopsy Specimen Adequacy in the United States and Canada: A Multicenter Study.

Objectives

Methods

Results

Conclusions

Publications

Trends in Bone Marrow Sampling and Core Biopsy Specimen Adequacy in the United States and Canada: A Multicenter Study.

Similar Datasets

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