The impact of BMI on clinical progress, response to treatment, and disease course in patients with differentiated thyroid cancer.

ABSTRACT:

Introduction

Obesity is a serious health problem worldwide, particularly in developed countries. It is a risk factor for many diseases, including thyroid cancer. The relationship between obesity and prognostic factors of thyroid cancer is unclear.

Aims

We sought to ascertain the relationship between body mass index (BMI) and clinicopathological features increasing the risk of poor clinical course, treatment response, and clinical outcome in patients with differentiated thyroid cancer (DTC).

Subjects & methods

The study included 1181 patients with DTC (88% women and 12% men) treated at a single center from 2000 to 2016. BMI before surgery and aggressive clinicopathological features, according to the American Thyroid Initial Risk stratification system, were analyzed. Th

SUBMITTER: Gasior-Perczak D 

PROVIDER: S-EPMC6166948 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature