Age-specific global epidemiology of hydrocephalus: Systematic review, metanalysis and global birth surveillance.

ABSTRACT:

Background

Hydrocephalus is a debilitating disorder, affecting all age groups. Evaluation of its global epidemiology is required for healthcare planning and resource allocation.

Objectives

To define age-specific global prevalence and incidence of hydrocephalus.

Methods

Population-based studies reporting prevalence of hydrocephalus were identified (MEDLINE, EMBASE, Cochrane, and Google Scholar (1985-2017)). Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed. Two authors reviewed abstracts, full text articles and abstracted data. Metanalysis and meta-regressions were used to assess associations between key variables. Heterogeneity and publication bias were assessed. Main outcome of interest was hydrocephalus prevalence among pedi

SUBMITTER: Isaacs AM 

PROVIDER: S-EPMC6166961 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature