Dermatologic manifestations of solid organ transplantation-associated graft-versus-host disease: A systematic review.

ABSTRACT: BACKGROUND:Graft-versus-host-disease (GVHD) after solid organ transplantation (SOT) is extremely rare. OBJECTIVE:To investigate the dermatologic manifestations and clinical outcomes of SOT GVHD. METHODS:Systematic literature review of SOT GVHD. RESULTS:After full-text article review, we included 61 articles, representing 115 patients and 126 transplanted organs. The most commonly transplanted organ was the liver (n = 81). Among 115 patients, 101 (87.8%) developed skin involvement. The eruption appeared an average of 48.3 days (range, 3-243 days) posttransplant and was pruritic in 5 of 101 (4.9%) cases. The eruption was described as morbilliform in 2 patients (1.9%), confluent in 6 (5.9%), and desquamative in 4 (3.9%) cases. In many cases, specific dermatologic descriptions were lacking. Th

SUBMITTER: Kim GY 

PROVIDER: S-EPMC6167008 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature