Continuous Vital Sign Analysis to Predict Secondary Neurological Decline After Traumatic Brain Injury.

ABSTRACT: Background: In the acute resuscitation period after traumatic brain injury (TBI), one of the goals is to identify those at risk for secondary neurological decline (ND), represented by a constellation of clinical signs that can be identified as objective events related to secondary brain injury and independently impact outcome. We investigated whether continuous vital sign variability and waveform analysis of the electrocardiogram (ECG) or photoplethysmogram (PPG) within the first hour of resuscitation may enhance the ability to predict ND in the initial 48 hours after traumatic brain injury (TBI). Methods: Retrospective analysis of ND in TBI patients enrolled in the prospective Oximetry and Noninvasive Predictors Of Intervention Need after Trauma (ONPOINT) study. ND was defin

SUBMITTER: Melinosky C 

PROVIDER: S-EPMC6167472 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature