Joint Reconstruction of Activity and Attenuation in Time-of-Flight PET: A Quantitative Analysis.

ABSTRACT: Methods for joint activity reconstruction and attenuation reconstruction of time-of-flight (TOF) PET data provide an effective solution to attenuation correction when no (or incomplete or inaccurate) information on attenuation is available. One of the main barriers limiting use of these methods in clinical practice is their lack of validation in a relatively large patient database. In this contribution, we aim to validate reconstruction performed with maximum-likelihood activity reconstruction and attenuation registration (MLRR) in a whole-body patient dataset. Furthermore, a partial validation (because the scale problem of the algorithm is avoided for now) of reconstruction performed with maximum-likelihood activity and attenuation (MLAA) is also provided. We present a quantitative compar

SUBMITTER: Rezaei A 

PROVIDER: S-EPMC6167531 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature