Transcriptomic response to parasite infection in Nile tilapia (Oreochromis niloticus) depends on rearing density.

ABSTRACT:

Background

Captive animal populations, be it for food production or conservation programmes, are often maintained at densities far beyond those in natural environments, which can have profound effects on behaviour, immune and stress levels, and ultimately welfare. How such alterations impact transcriptional responses to pathogen infection is a 'different kettle of fish' and remains poorly understood. Here, we assessed survival and gene expression profiles of infected fish reared at two different densities to elucidate potential functional genomic mechanisms for density-related differences in disease susceptibility.

Results

Utilising a whole-transcriptome sequencing (RNAseq) approach, we demonstrate that rearing density in tilapia (Oreochromis niloticus) significantly impacts

SUBMITTER: Ellison AR 

PROVIDER: S-EPMC6167859 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature