Effect of Pneumatic Tubing System Transport on Platelet Apheresis Units.

ABSTRACT: Platelet apheresis units are transfused into patients to mitigate or prevent bleeding. In a hospital, platelet apheresis units are transported from the transfusion service to the healthcare teams via two methods: a pneumatic tubing system (PTS) or ambulatory transport. Whether PTS transport affects the activity and utility of platelet apheresis units is unclear. We quantified the gravitational forces and transport time associated with PTS and ambulatory transport within our hospital. Washed platelets and supernatants were prepared from platelet apheresis units prior to transport as well as following ambulatory or PTS transport. For each group, we compared resting and agonist-induced platelet activity and platelet aggregate formation on collagen or von Willebrand factor (VWF) under shear, p

SUBMITTER: Zilberman-Rudenko J 

PROVIDER: S-EPMC6168073 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature